

Price: $399.99
Access Duration: 30 Months
Deliverables: 100 Hours of AAPA Category 1 Self-Assessment CME Credit, 17 Hours of Video Content, 1,672 Board-Style Questions
Successfully navigating the PANRE requires more than just clinical knowledge; it requires a strategic understanding of how the NCCPA weights each organ system. In 2026, the blueprint remains the definitive guide for your preparation. Attempting to master every rare orphan disease is a common pitfall that ignores the statistical reality of the exam.
The PANRE Review Course was designed by PAs for PAs to align specifically with these weightings. By focusing your limited study time on high-yield categories, you maximize your score while earning 100 hours of AAPA Category 1 CME.
The Blueprint Breakdown: Where the Points Are
The NCCPA content blueprint is not a suggestion; it is a roadmap. If you ignore the percentages, you are essentially guessing which topics will appear on your exam. Here is how the organ systems are currently distributed for the PANRE:
- Cardiovascular System: 13%
- Pulmonary System: 10%
- Gastrointestinal System/Nutrition: 9%
- Musculoskeletal System: 9%
- Eyes, Ears, Nose, and Throat (EENT): 7%
- Endocrine System: 7%
- Genitourinary System: 7%
- Neurologic System: 7%
- Reproductive System (Male and Female): 7%
- Infectious Diseases: 6%
- Psychiatry/Behavioral Science: 5%
- Dermatologic System: 5%
- Hematologic System: 3%


High-Yield Focus: Internal and Family Medicine Core
Combined, Cardiovascular, Pulmonary, GI, and Musculoskeletal systems account for 41% of your exam. This is why our PANRE Review Course emphasizes these Internal Medicine and Family Medicine core competencies. You cannot pass this exam by being "okay" at Cardiology; you must be proficient.
The weightings also indicate where not to spend excessive time. While Hematology (3%) is important for clinical practice, spending a week memorizing the nuances of rare thalassemias at the expense of Heart Failure (13%) is a poor use of resources. Our course provides 17 hours of video lecture that directly mirrors this blueprint, ensuring you stay focused on the "big hitters."
Clinical Practice: Assessing High-Yield Knowledge
The following vignettes represent the level of detail and clinical reasoning required for the PANRE. Test your knowledge on these high-yield blueprint topics.
Scenario 1: Cardiology (13%)
Your patient is a 68-year-old male with a history of hypertension and hyperlipidemia who presents to the clinic complaining of increased dyspnea on exertion and a dry cough when lying down at night. On physical exam, you note a displaced apical impulse and 2+ bilateral pitting edema in the lower extremities. Vital signs are: BP 155/90 mmHg, HR 88 bpm, RR 18, SaO2 94% on room air. An echocardiogram reveals an ejection fraction of 35%.
Which of the following medication classes is indicated to improve mortality in this patient?
A. Loop Diuretics
B. Calcium Channel Blockers
C. ACE Inhibitors
D. Digoxin
Scenario 2: Pulmonary (10%)
Your patient is a 24-year-old female with a history of mild intermittent asthma who presents for a follow-up. She reports using her albuterol inhaler four days a week over the last month. She has been awakened by wheezing three times in the past thirty days. Her FEV1 is 82% of predicted.
What is the most appropriate next step in the management of this patient’s asthma?
A. Maintain current therapy with PRN albuterol
B. Add a low-dose inhaled corticosteroid (ICS)
C. Start a long-acting beta-agonist (LABA) as monotherapy
D. Add an oral leukotriene receptor antagonist
Explanations and Clinical Justification
Scenario 1 Correct Answer: C. ACE Inhibitors
ACE Inhibitors (or ARBs/ARNIs) are the correct choice because they have been definitively proven to reduce mortality and morbidity in patients with Heart Failure with reduced Ejection Fraction (HFrEF). They inhibit the renin-angiotensin-aldosterone system, preventing maladaptive cardiac remodeling.
- Loop Diuretics (A) are essential for symptom management (edema, congestion) but do not provide a mortality benefit.
- Calcium Channel Blockers (B), specifically non-dihydropyridines, should be avoided in HFrEF as they can worsen heart failure.
- Digoxin (D) may reduce hospitalizations but does not improve survival rates.
Scenario 2 Correct Answer: B. Add a low-dose inhaled corticosteroid (ICS)
The correct answer is to add a low-dose inhaled corticosteroid (ICS). This patient meets the criteria for mild persistent asthma (symptoms > 2 days/week and nocturnal awakenings 3–4 times/month). Low-dose ICS is the preferred controller therapy to reduce airway inflammation and prevent exacerbations.
- Maintaining current therapy (A) is inappropriate as she is currently uncontrolled.
- LABA monotherapy (C) is contraindicated in asthma due to an increased risk of asthma-related death.
- Leukotriene receptor antagonists (D) are an alternative but are generally considered second-line to ICS.
Maximizing Your CME Budget with Gift Card Add-Ons
Preparing for the PANRE is a significant professional commitment. We believe that your educational budget should work harder for you. Our PANRE Review Course includes an optional gift card add-on feature.
When you purchase the course, you can add an Amazon or Apple Gift Card ranging from $100 to $1,500. This allows you to bundle your educational expenses with a tool for further enrichment: whether that is a new iPad for clinical reference or medical equipment for your practice. The total price is reflected on a single invoice, providing an efficient way to utilize your employer-sponsored CME allowance.


The 150-Credit Bonus
One of the most efficient aspects of this course is how the NCCPA handles self-assessment credits. While the course provides 100 hours of AAPA Category 1 CME, the NCCPA applies a 50% weighting bonus when you log these specific credits for certification maintenance. This means completing this one course satisfies 150 credits toward your maintenance requirements, significantly reducing your administrative burden.
Whether you are a Physician Assistant in Family Medicine, Internal Medicine, or a specialized field like Orthopedics or Dermatology, the core blueprint remains your common hurdle. Use our 1,672 board-style questions and 17 hours of clinical video to ensure you aren't just studying, but studying the right material.
Quick Summary of Course Benefits:
- Accreditation: 100 Hours AAPA Category 1 Self-Assessment CME.
- Value: One purchase can satisfy up to 150 NCCPA credits.
- Content: 1,672 board-style questions and 17 hours of blueprint-aligned video.
- Flexibility: 30 months of access on any device.
- Incentives: $100-$1500 Amazon or Apple Gift Card add-ons available.











