

Course Title: PANRE Review Course
Price: Starting at $650.00
Credits: 100 Category 1 AAPA Credits
Access: Lifetime
Deliverables: Comprehensive Digital Course, Practice Exams, Digital/Physical Study Guides
Internal Medicine represents the largest portion of the NCCPA blueprint for both the PANCE and the PANRE. For the practicing Physician Assistant, staying current with the evolving guidelines in cardiology, pulmonology, and endocrinology is not just a requirement for recertification; it is a clinical necessity for patient safety. Our PANRE Review Course is designed to provide high-yield, concise clinical information that mirrors the complexity of internal medicine practice while fulfilling your entire 100-hour Category 1 CME cycle in a single purchase.
Mastering the Internal Medicine Blueprint
The NCCPA blueprint weights Cardiology at 13%, Pulmonology at 10%, and GI/Nutrition at 11%. When you factor in Endocrinology (6%), Infectious Disease (6%), and Renal (3%), over half of your exam content is rooted in Internal Medicine. Success on the PANRE or PANRE-LA requires a shift from rote memorization to clinical application. You must be able to differentiate between stable and unstable angina, manage acute COPD exacerbations, and recognize the metabolic derangements of DKA.
Our pance prep courses and PANRE review materials focus on level 2 and level 3 assessment topics. This means you won't just identify a disease; you will manage it. We provide the diagnostic pearls and first-line treatment protocols used in everyday hospitalist and outpatient medicine.


100 Hours of Category 1 AAPA Credit
The PANRE Review Course offers an efficient pathway to completing your CME requirements. This course is designated for 100 hours of Category 1 AAPA credit. By completing this single program, you satisfy the biannual requirement for the NCCPA without needing to piece together smaller, less relevant modules.
While our Pharmacology Course also offers Category 1 AAPA credit, the 100-hour block is specifically attributed to the comprehensive PANRE Review Course. This ensures that your study time serves a dual purpose: preparing you for a high-stakes exam and securing your professional credentials.
CME with Gift Cards: Maximizing Your Education Budget
Many PAs receive a yearly CME stipend that must be used or lost. To help you further enrich your professional development, we offer cme gift cards as optional add-ons to our packages. During checkout, you can choose to add an Amazon or Apple Gift Card ranging from $100 to $1500 to your purchase.
It is important to understand that these are not free gifts. They are educational add-ons that are included in the total purchase price of your CME package. This allows you to use your professional development funds to acquire necessary tools: such as medical tablets, reference books, or clinical software: through Amazon or Apple, while simultaneously receiving your 100 hours of Category 1 AAPA credit.


Clinical Assessment: Internal Medicine Practice Questions
Test your knowledge with these high-yield clinical vignettes. Each scenario follows the format and difficulty level expected on the PANRE.
Vignette 1: Cardiology
Your patient is a 64-year-old male with a history of hypertension and tobacco use who presents to the emergency department with a 2-hour history of substernal chest pressure that radiates to his left jaw. His blood pressure is 154/92 mmHg, HR is 98 bpm, and SaO2 is 96% on room air. The initial EKG shows 2mm ST-segment elevation in leads II, III, and aVF.
Which of the following is the most appropriate next step in management?
A. Perform a bedside exercise stress test
B. Administer 325mg of Aspirin and activate the cardiac catheterization lab
C. Order a D-dimer and CT Pulmonary Angiography
D. Administer IV Metoprolol and repeat EKG in 30 minutes
Correct Answer: B. Administer 325mg of Aspirin and activate the cardiac catheterization lab
Explanation: This patient is presenting with a ST-Elevation Myocardial Infarction (STEMI) involving the inferior wall. The immediate management involves dual antiplatelet therapy (starting with non-enteric coated aspirin) and immediate reperfusion therapy. Percutaneous Coronary Intervention (PCI) is the gold standard and must be initiated as quickly as possible to minimize myocardial necrosis. Stress testing is contraindicated in the acute setting of an MI. CTPA is used for suspected PE, not STEMI. Beta-blockers should be used with caution in the acute phase of an MI, especially if there is a risk of cardiogenic shock or if the heart rate is already compensated.
Vignette 2: Pulmonology
Your patient is a 72-year-old female with a 50 pack-year smoking history and known COPD who presents with increased shortness of breath and productive cough for three days. She is using her rescue inhaler every 2 hours without significant relief. On exam, she has diffuse wheezing and is using accessory muscles to breathe. Her SaO2 is 89% on room air.
In addition to supplemental oxygen and nebulized bronchodilators, which medication has been shown to reduce the duration of the exacerbation and improve lung function?
A. Daily Azithromycin
B. Intravenous Theophylline
C. Systemic Corticosteroids
D. Inhaled Nedocromil
Correct Answer: C. Systemic Corticosteroids
Explanation: Systemic corticosteroids (e.g., Prednisone 40mg daily for 5 days) are a cornerstone of COPD exacerbation management. They have been shown to shorten recovery time, improve FEV1, and reduce the risk of early relapse. Azithromycin is sometimes used for its anti-inflammatory properties in chronic management but is not the primary treatment for acute improvement of lung function in an exacerbation unless a bacterial infection is suspected (and even then, steroids are concurrent). Theophylline has a narrow therapeutic index and is rarely used due to toxicity. Nedocromil is a mast cell stabilizer used for asthma prophylaxis, not acute COPD exacerbations.
Vignette 3: Endocrinology
Your patient is a 28-year-old female with Type 1 Diabetes Mellitus who is brought to the clinic feeling weak and nauseated. She reports a recent "stomach flu" and hasn't been taking her insulin consistently because she hasn't been eating. Her skin is flushed and dry, and she has deep, rapid respirations. A fingerstick glucose reads "High" (>500 mg/dL).
What is the most likely additional finding on a metabolic panel for this patient?
A. Metabolic Alkalosis
B. Increased Anion Gap
C. Hypocalcemia
D. Normal Serum Ketones
Correct Answer: B. Increased Anion Gap
Explanation: This patient is presenting with Diabetic Ketoacidosis (DKA), likely triggered by an infection and omission of insulin. DKA is characterized by a triad of hyperglycemia, ketosis, and metabolic acidosis. The acidosis is an increased anion gap metabolic acidosis due to the accumulation of beta-hydroxybutyrate and acetoacetate. Metabolic alkalosis would not be expected. Serum ketones would be elevated, not normal. While potassium levels can shift, hypocalcemia is not a defining feature of acute DKA.
Prepare Today for Your Professional Future
The PANRE Review Course at CME Review Courses provides the most efficient way to master Internal Medicine while securing your 100 hours of Category 1 AAPA credit. Whether you are preparing for the traditional PANRE or the PANRE-LA, our content is tailored to give you the clinical confidence you need.
Maximize your professional allowance by choosing one of our cme gift cards add-on packages. Select from Amazon or Apple gift cards valued between $100 and $1500 to ensure you have the tools necessary for your continued education.
And for PA students or early-career clinicians looking to crush the PANCE and EOR exams, check out PAtopia — our all-in-one app with 11,000+ board-style questions spanning every rotation. Visit cmereviewcourses.com/patopia-new-student-section/ to learn more.












