

Preparing for the PANRE or PANRE-LA requires a strategic approach that mirrors the clinical realities of modern practice. The NCCPA Blueprint is the definitive guide for exam preparation, emphasizing organ systems and clinical task areas that Physician Assistants encounter daily. Our PANRE Review Course is designed to provide maximum efficiency for your study time and your professional development budget.
Course Logistics:
- Price: $399.99
- Duration of Access: 30 Months
- CME Credits: 100 Hours of AAPA Category 1 Credit
- Deliverables: 1,672 board-style review questions and 17 hours of high-yield video content.
Alignment with the NCCPA Blueprint
The NCCPA Blueprint dictates the weight of each medical category on your exam. For instance, the Cardiovascular System remains a cornerstone of the assessment, typically accounting for 13% of the exam content. Our course ensures that your preparation time is proportional to these weightings. We provide intensive coverage of Cardiology, Emergency Medicine, and Internal Medicine, ensuring you are prepared for both the breadth of general practice and the depth of acute care scenarios.
Proper documentation is not just a clinical requirement; it is a clinical task area tested by the NCCPA. Understanding how to document history, physical exam findings, and management plans accurately is essential for both your certification and your liability protection. Our review materials integrate these practical elements into every module.
Cardiology: The 13% Content Powerhouse


Cardiovascular disease is the most heavily weighted organ system on the PANRE. Our curriculum breaks down complex electrophysiology, valvular disorders, and heart failure management into digestible, exam-focused pearls. We prioritize the recognition of classic ECG patterns and the implementation of current ACC/AHA guidelines for hypertension and lipid management.
Emergency Medicine and Internal Medicine


Whether you practice in a rural ER or a busy metropolitan hospitalist service, the PANRE tests your ability to stabilize acute patients and manage chronic comorbidities. Our Emergency Medicine CME Package and Internal Medicine content focus on high-acuity presentations like sepsis, acute respiratory failure, and metabolic derangements. We emphasize the "must-not-miss" diagnoses that are frequent flyers on the NCCPA Blueprint.
The Gift Card Perk: Enriching Your Professional Education


We understand that PAs often have CME funds that must be used within a specific fiscal window. To help you further your education, we offer CME with Amazon and Apple Gift Card add-ons. You can add a gift card ranging from $100 to $1,500 to your purchase.
This allows you to acquire the hardware, such as an iPad for mobile charting, or the reference texts you need to stay current in your specialty. It is an efficient way to utilize your employer-provided CME allowance while securing 100 hours of AAPA Category 1 credit.
Clinical Assessment: Practice Scenarios
Use the following vignettes to test your knowledge of the NCCPA Blueprint categories in Cardiology, Emergency Medicine, and Internal Medicine.
Scenario 1: Cardiology
Your patient is a 64-year-old male with a history of hypertension and tobacco use who presents to the clinic for a routine follow-up. He reports recent episodes of "chest tightness" that occur when he is mowing his lawn and resolve after five minutes of rest. He denies syncope, orthopnea, or lower extremity edema. His vital signs are: BP 148/92, HR 78, RR 16, SaO2 98% on room air. Physical exam reveals a normal S1 and S2 with no murmurs or gallops.
Which of the following is the most appropriate next step in the diagnostic workup for this patient?
A) Coronary Angiography
B) Exercise Stress Echocardiogram
C) 24-hour Holter Monitor
D) Troponin I and CK-MB levels
Scenario 2: Emergency Medicine


Your patient is a 28-year-old female brought to the Emergency Department by EMS after being found unresponsive in a park. On arrival, she is lethargic but arousable to painful stimuli. Her vital signs are: BP 102/64, HR 52, RR 6, SaO2 88% on room air. Physical exam reveals pinpoint pupils and track marks on her bilateral antecubital fossae.
After securing the airway, which of the following is the most immediate pharmacological intervention?
A) Flumazenil
B) Naloxone
C) Dextrose 50%
D) Atropine
Scenario 3: Internal Medicine
Your patient is a 72-year-old female hospitalized for a hip fracture repair. On postoperative day three, she develops sudden onset shortness of breath and pleuritic chest pain. Her vital signs are: BP 110/70, HR 112, RR 24, SaO2 91% on 2L nasal cannula. Her surgical site is clean, but her right calf is erythematous and tender to palpation.
Which of the following is the gold standard for confirming the suspected diagnosis?
A) D-dimer assay
B) Ventilation-Perfusion (V/Q) scan
C) CT Pulmonary Angiography (CTPA)
D) Venous Duplex Ultrasound
Explanations and Rationales
Scenario 1: Cardiology
Correct Answer: B) Exercise Stress Echocardiogram
The patient’s presentation is classic for stable angina, characterized by predictable chest discomfort with exertion that is relieved by rest. In a patient with an intermediate pre-test probability of coronary artery disease (CAD) who is able to exercise and has a baseline ECG that is likely interpretable, an exercise stress echocardiogram is an appropriate initial non-invasive test to evaluate for inducible ischemia.
- Coronary Angiography (A) is an invasive "gold standard" typically reserved for patients with high-risk features on non-invasive testing or unstable presentations.
- Holter Monitor (C) is used for evaluating palpitations or suspected arrhythmias, not exertional ischemia.
- Troponins (D) are markers of acute myocardial necrosis; they are not indicated in a stable outpatient setting where the symptoms have resolved.
Scenario 2: Emergency Medicine
Correct Answer: B) Naloxone
The clinical triad of coma, respiratory depression (RR 6), and miosis (pinpoint pupils) is pathognomonic for opioid overdose. Naloxone is a competitive opioid antagonist that should be administered immediately to reverse respiratory depression.
- Flumazenil (A) is used for benzodiazepine overdose but carries a high risk of inducing seizures in chronic users or mixed ingestions.
- Dextrose (C) is indicated for hypoglycemia; while it may be part of a "coma cocktail," the respiratory rate and pupils point specifically to opioids.
- Atropine (D) is used for symptomatic bradycardia, but the bradycardia in this patient is secondary to respiratory failure and hypoxia caused by the opioid.
Scenario 3: Internal Medicine
Correct Answer: C) CT Pulmonary Angiography (CTPA)
The patient presents with signs and symptoms of a Pulmonary Embolism (PE) following major orthopedic surgery, which is a significant risk factor. CT Pulmonary Angiography (CTPA) is currently the preferred diagnostic "gold standard" (more accurately, the first-line definitive imaging) for PE due to its high sensitivity and specificity.
- D-dimer (A) has a high negative predictive value but is non-specific, especially in a postoperative patient where it will likely be elevated regardless of a clot.
- V/Q scan (B) is an alternative when CTPA is contraindicated (e.g., renal failure or contrast allergy).
- Venous Duplex (D) can confirm a DVT but does not confirm the presence of a PE.
Maximize Your CME Investment
Earning your 100 hours of AAPA Category 1 credit doesn't have to be a chore. By choosing a course that aligns specifically with the NCCPA Blueprint, you ensure that every hour spent studying is an hour spent moving closer to recertification. Our PANRE Review Course provides the content you need with the financial flexibility you want. Use your CME funds to secure your future and get the gift card add-on you deserve.










































