Price: $499.99. Access: 30 months. CME: Up to 100 AAPA Category 1 credits from the PANRE Clinical Review Module only, not the Pharmacology course. The separate Pharmacology course is also $499.99. Practice: 2,500+ board-style questions, five full-length 240-question mock exams, and 15 body-system modules. Amazon and Apple Gift Card add-ons range from $100 to $1,500; they are paid add-ons added to the purchase price, not free gifts.
The PANRE Review Course includes 1,810 questions across its 15 modules and 1,200 questions across its five mock exams. The course also provides answer rationales with cited sources, a PANRE Readiness Dashboard, and online access on a phone, tablet, or computer without a download. Its explanations are rewritten to current 2023–2025 clinical guidelines and individually cited.
To earn credit, review all module content, complete the post-test with a score of 70% or higher, and complete the activity evaluation. You may retake missed questions. A certificate stating your precise credit is issued when both requirements are complete; claim only credit commensurate with your participation.
The activity is Comprehensive Clinical Review for Practicing PAs: 2026–27 Enduring CME Activity, AAPA reference CME-2016187. Approval is valid 8/26/2026 to 8/26/2027; release date is 8/26/2026 and expiration date is 8/26/2027. The accreditation statement is at the program level: it designates the full 14-module program for 468.75 AAPA Category 1 CME credits. That program-level amount is not the credit value of this individual PANRE module. Faculty is Jeremy Boroff, MPAS, PA-C, sole faculty, with no relevant financial relationships to disclose. The activity received no commercial support.
Mistake 1: Memorizing topics without tagging the performance expectation
The NCCPA Blueprint does not only list conditions. It also identifies the performance expectation at which a disease may be assessed:
- History & Physical: Given a stated or differential condition, know the associated signs, symptoms, history, examination findings, complications, and risk factors.
- Diagnosis: Given clinical findings and appropriate studies, determine the most likely diagnosis.
- Intervention (Basic): Manage a straightforward presentation, including referral when appropriate, and know complications of the intervention.
- Intervention (Complex): Manage a condition made complex by other factors or increasing severity.
A common mistake is to review a disease as a collection of facts without asking what task the exam is testing. When you miss a question, record both the topic and the expectation, for example: topic: cauda equina syndrome; expectation: Intervention (Basic). That two-part entry can help you distinguish a content gap from difficulty interpreting what the question asks.
The PANRE Readiness Dashboard tracks attempted-versus-correct responses with a per-topic breakdown. The course’s answer explanations walk through why the correct option is best, giving you practice distinguishing a diagnostic task from a management task.
Mistake 2: Giving all 15 modules the same study weight
The NCCPA Blueprint gives approximate organ-system allocations. Percentages may vary slightly and are not exact per-exam question counts. Use them to understand relative emphasis, not to predict the exact composition of your exam.
| Organ system | Approximate share of the exam | Course module questions |
|---|---|---|
| Cardiovascular | 12% | 211 |
| Dermatologic | 5% | 218 |
| Endocrine | 8% | 65 |
| Eyes, Ears, Nose, and Throat (EENT) | 8% | 181 |
| Gastrointestinal and/or Nutrition | 10% | 137 |
| Genitourinary | 5% | 104 |
| Hematologic | 4% | 66 |
| Infectious Diseases | 7% | 67 |
| Musculoskeletal | 8% | 130 |
| Neurologic | 5% | 107 |
| Psychiatry/Behavioral Science | 7% | 67 |
| Pulmonary | 10% | 115 |
| Renal | 4% | 70 |
| Reproductive | 5% | 202 |
| Emergent Topics (Legal, Ethical, DEI) | 2% | 70 |
The course’s module question counts and the exam’s approximate allocations serve different purposes: the table does not imply that a larger course question count means a larger exam share. Use the NCCPA percentages to understand the exam’s distribution and the module bank to work across its topics.
Mistake 3: Treating low-percentage modules as optional
The six modules at 5% or less (Dermatology, Genitourinary, Neurologic, Reproductive, Hematologic, and Renal) add up to about 28% of the exam. That is more than double the largest single organ system, Cardiovascular at 12%. Skipping the “small” systems is not a small decision.
Also read the Emergent Topics label carefully. The NCCPA Blueprint defines this 2% category as Legal, Ethical, and DEI. It is not an emergency medicine category, so do not budget emergency-department-style study time for that line item.
CME gift cards
Amazon and Apple add-ons are paid options from $100 to $1,500, added to the course price at checkout. They are a budgeting choice, not free gifts, discounts, or rebates. The add-on itself earns no CME credit; credit comes from completing the PANRE Clinical Review Module.
Checkout tiers are offered in $100 increments per brand; Amazon also lists a $150 tier. The card is emailed within 2–3 business days of purchase, and you do not have to finish the course first. Gift card packages cannot be refunded once emailed, so confirm your employer’s CME policy before checkout. The site is not affiliated with Amazon or Apple.
Buy two or more CME courses and a 20% discount comes off every course automatically. Gift card add-ons stay at face value, and you can add one to every course you buy.
Clinical vignette: Myasthenia gravis
You see a 58-year-old adult in an outpatient clinic with several weeks of fluctuating ptosis and diplopia. The symptoms are mild in the morning and clearly worse by evening. The patient reports new mild difficulty swallowing solids and proximal arm weakness when brushing their hair. There is no pain or sensory change. Reflexes are normal and symmetric. There has been no recent diarrheal illness or autonomic symptoms. Vital signs are normal, and there is no respiratory distress.
This is a Diagnosis-level question: which is the most appropriate next step in evaluation?
A. Order acetylcholine receptor antibody testing to confirm myasthenia gravis.
B. Start pyridostigmine and skip testing.
C. Obtain MRI of the brain to rule out stroke.
D. Order nerve conduction studies for a demyelinating polyneuropathy.
Correct answer: Order acetylcholine receptor antibody testing to confirm myasthenia gravis. The fluctuating, fatigable ptosis and diplopia, bulbar symptoms, and proximal weakness support myasthenia gravis; antibody testing is the appropriate confirmatory step. Starting pyridostigmine without establishing the diagnosis provides symptomatic treatment rather than confirmation and may muddy serology. MRI for stroke is not the best fit for fluctuating, fatigable, symmetric findings over weeks. Guillain-Barré syndrome and CIDP do not produce this characteristic fatigable ptosis-and-diplopia pattern.
Real-world exam note: When a stem gives you a characteristic pattern and asks for the next step in evaluation, it tests the Diagnosis expectation, not Intervention. Choose the test that confirms the pattern, not treatment that may mask it. New bulbar symptoms also warrant clinical attention to swallowing and breathing.
Review the course and NCCPA resources
Explore the PANRE Review Course and CME add-ons or try the free PANRE test drive. A money-back guarantee applies if you do not pass on your first attempt after purchasing the full course; see the terms.
For the official topic list and certification information, consult the NCCPA Blueprint topic list, NCCPA maintain certification page, and NCCPA key dates. Traditional PANRE and PANRE-LA share the same NCCPA content Blueprint; the PANRE-LA Review Course CME Package and PANRE/PANRE-LA Review Exams with Gift Card add-on are format-specific options.
Looking for pance prep courses? Explore PAtopia on the web, PAtopia for iOS, and PAtopia on Google Play.
Nurse practitioners should verify acceptance of AAPA Category 1 credit with their state board of nursing; acceptance varies by state. For physicians, the activity meets AAPA Category 1 requirements, which counts as Category 2 for physicians’ own reporting.
About the author
Jeremy Boroff, MPAS, PA-C, is an Emergency Medicine PA with 24 years of clinical experience, a PA educator, author, and CME developer. He is the sole faculty member for this activity and has no relevant financial relationships to disclose.